[Journal] Flexible transparent neural interface device work is published. - Kang Lab @ AEDRG

Our recent research efforts on developing flexible and transparent microelectrodes for more efficient hybrid electro-optical neural interfaces has been published in Advanced Functional Materials (IF: 18.808, top 4% journal in Materials Science, Multidisciplinary) on November 21st, 2021. This work was mainly led by our former graduate, Woongki Hong with the support from our lab & group members and an international collaboration with the Department of Neuroscience, Uppsala University, Sweden (Prof. Anna Rostedt Punga’s lab). We expect that our effort can open up not only new bioelectronics interfaces, but also various flexible and transparent electronics applications including wearable electronics. Congratulations!

Title: Ultrathin Gold Microelectrode Array using Polyelectrolyte Multilayers for Flexible and Transparent Electro-Optical Neural Interfaces

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Abstract: Electro-optical neural interface technologies provide great potential and versatility in neuroscience research. High temporal resolution of electrical neural recording and high spatial resolution of optical neural interfacing such as calcium imaging or optogenetics complimentarily benefit the way information is accessed from neuronal networks. To develop a hybrid neural interface platform, it is necessary to build transparent, soft, flexible microelectrode arrays (MEAs) capable of measuring electrical signals without light-induced artifacts. In this work, flexible and transparent ultrathin (<10 nm) gold MEAs are developed using a biocompatible polyelectrolyte multilayer (PEM) metallic film nucleation-inducing seed layer. With the polymer seed layer, the thermally evaporated ultrathin gold film shows good conductivity while providing high optical transmittance and excellent mechanical flexibility. In addition, strong electrostatic interaction via the PEM alters the electrode-electrolyte interfaces, thereby reducing the electrode impedance and baseline noise level. With a simple modification of the fabrication process of the MEA using biocompatible materials, both excellent transmittance, and electrochemical interface characteristics are achieved, which is promising for efficient electro-optical neural interfaces.

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